Neotame and other artificial sweeteners

In a previous report I pointed out some of the scientific literature evidence of the harmful effects of aspartame (NutraSweet, Equal), saccharin, and sucralose (Splenda). Now let’s take a look at the new and improved aspartame called Neotame,[i] and then a quick look at the others: acesulfame-K, cyclamate and alitame.

Neotame (the new aspartame) is not aspartame

It is interesting that an online scientific literature search at for “artificial sweeteners” results in 222,587 search results.

Just because aspartame has been shown to worsen depression,[ii] disrupt gut microbiome,[iii] cause glucose intolerance,[iv] contribute to weight gain,[v] [vi] be neurotoxic[vii] and even promote brain cancer,[viii] contribute to autoimmune thyroiditis,[ix] and lead to formaldehyde bio-accumulation in rats,[x] does not mean that neotame will have the same adverse effects on health. Moreover, aspartame is unstable if heated too long so it is not good to use in baking or cooking and it decomposes when stored in liquids. Does neotame have similar unwanted properties?

Let’s look at Neotame more closely and see what precautions we should be aware of if any.

Neotame is known to be approximately 13,000 times sweeter than sucrose (table sugar) and 30-40 times sweeter than aspartame.[xi] Neotame was developed in order to eliminate the PKU (phenylketonuria) warning that aspartame carries, by adding 3,3-dimethylbutyraldehyde to aspartame to reduce phenylalanine production in the body. 3-di-methylbutyl, which can be found on th